Heart disease occurs when the coronary arteries become partially blocked or clogged. This blockage limits the flow of blood through the coronary arteries, the major arteries supplying oxygen-rich blood to the heart. The coronary arteries expand when the heart is working harder and needs more oxygen. If the arteries are unable to expand, the heart is deprived of oxygen (myocardial ischaemia). When the blockage is limited, chest pain or pressure called angina may occur. When the blockage cuts off the blood flow, the result is heart attack (myocardial infarction or heart muscle death).
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